

Orb of Annulment respects the meta-crafting mods.Using a fossil + resonator on an item with a meta-crafting mod (Prefixes Cannot Be Changed or Cannot roll Caster Modifiers) will ignore that mod and overwrite existing prefixes and suffixes ignoring any restrictions. Using an essence on an item with a meta-crafting mod (Prefixes Cannot Be Changed or Cannot roll Caster Modifiers) will ignore that mod and overwrite existing prefixes and suffixes ignoring any restrictions. Essence ignores the meta-crafting mod.The risk of adding bad suffixes with no easy way to remove them is also not something I would accept. Also, since your 'cannot change prefix' mod is removed upon scouring, you'll need to add it on again afterward to protect your mod against your next chaos application and so on for each chaos. Chaos spam is more random and cost-inefficient than the alt-aug-regal-scour or alc-scour methods. Note that the "prefixes cannot be changed" is also a suffix and will be removed. If you put 'prefixes cannot be changed' and use a Chaos Orb on the item, it will keep the prefixes and reroll new suffixes. Chaos Orb respects the meta-crafting mod.The better approach is where you have 3 desirable (and preferably, rare) prefixes on the item after scouring. This way, players can lock in modifiers without losing all the other modifiers. Implicit modifiers, quality, sockets, and links are not removed, as well as affixes protected by meta-crafting mods. Orb of Scouring removes all random modifiers from a magic or rare piece of equipment. Orb of Scouring respects the meta-crafting mod.The 'Prefixes Cannot Be Changed' is a also a suffix, so it will be rerolled. But are not protected against rerolls via essence, fossil, Maven's Orb, or Awakener's Orb. Note:Prefixes are protected against Chaos Orb, Orb of Annulment, Divine Orb, Veiled Chaos Orb, Harvest reforges and Orb of Scouring. This way the player can often limit the pool of possible mods so that outcome of the craft is almost guaranteed. Using the Prefixes Cannot Be Changed meta-crafting mod to combine multiple other meta-crafting mods allows for even more control of the item.
